Aedín Culhane is a Professor of Biomedical Sciences (Cancer Genomics) in the UL School of Medicine. She is a computational oncologist with expertise in multi-omics data integration, statistical genomics, clinical bioinformatics and genomics in oncology.  She has over 20 years’ experience in cancer genomics, of which over 15 years were in the Dana-Farber Cancer Institute and Harvard TH Chan School of Public Health in Boston, USA.  Her recent research focuses on algorithm development and integrative data of single cell molecular data in cancer to identify molecules that regulate and can be targeted during tumour development, progression, drug response and resistance.  She is a member of the Human Cell Atlas (https://www.humancellatlas.org ) project.   She is a leader in the Bioconductor (www.bioconductor.org) community, a global open source, open development software in R for genomics and an advocate for open source science.  

Professional Memberships: 

Member, The International Society for Computational Biology (ISCB), 2000-
Member, The American Association for Cancer Research (AACR), 2007-
Member, Dana-Farber/Harvard Cancer Center (DF/HCC) 2015-
Member, Bioconductor, Technical Advisory Board, 2014- present
Co-Chair, Bioconductor, Community Advisory Board, 2020- present
Member, Board of Directors, Massive Analysis and Quality Control Society (MAQC) Society, 2020-
Member, Scientific Advisory Board, Systems Biology Ireland (SBI), 2021-

Research Interests: 

Prof Culhane’s lab develops and applies mathematical, statistical and computational algorithms and tools to understand the trends, and changes that govern healthy and diseased cell states in cancer.  Read more about her research program on her lab website. 
 

POSTDOCTORAL TRAINING: 
Postdoc, University College Cork, Ireland  (Prof D. Higgins Lab), 2001-2003
Postdoc , University College Dublin, Ireland. (Prof D. Higgins Lab), 2003-2005
Research Associate, Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA  (Prof J Quackenbush lab), 2005-2011
Research Associate, Biostatistics and Computational Biology    Dana-Farber Cancer Institute, Boston, MA, USA (Prof J Quackenbush lab), 2005-2011


ACADEMIC APPOINTMENTS:
Adjunct Instructor, Rabb School of Continuing Studies, Brandeis University, 2008-2010
Research Scientist, Harvard School of Public Health, Boston, MA, 2011-2017 
Research Scientist, Dana-Farber Cancer Institute, Boston, MA, 2011-2017
Senior Research Scientist, Harvard School of Public Health, Boston, MA, 2017-2021
Senior Research Scientist, Dana-Farber Cancer Institute, Boston, MA, 2017-2021

ACADEMIC QUALIFICATIONS:

Ph.D. University of Manchester, UK.

B.Sc. (Hons, First Class), Industrial Biochemistry, University of Limerick

Publications

Please see  NCBI PubMed Bibliography, OrcID profile. Also a list of most recent publication including preprints is available on Google Scholar